5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide(CAS: 570403-04-2)

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide is a solid with a crystalline form. It has a molecular weight of approximately 652.3 g/mol and is soluble in organic solvents like DMSO and methanol. The compound exhibits moderate reactivity with nucleophiles. It is stable under normal conditions but should be stored away from moisture and heat.

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide is synthesized through multi-step organic synthesis involving the coupling of 2-chloronicotinamide with a thiazole derivative under the presence of a suitable catalyst such as a palladium complex. The reaction is typically carried out in an inert solvent like DMF or NMP under microwave heating to improve yield and selectivity.

5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide is primarily used in the pharmaceutical industry for its potential as an intermediate in drug development. It may also find applications in the polymer industry for its chemical properties.

When handling 5,6-Dichloro-N-(4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl)nicotinamide, proper personal protective equipment (PPE) such as gloves, safety goggles, and lab coat should be worn. It should be stored in a cool, dry place away from moisture and heat. In case of spill, it should be handled using appropriate spill cleanup materials and procedures. Always refer to a Safety Data Sheet (SDS) for specific handling and disposal instructions.