3-(1,1,2,2-Tetrafluoroethoxy)aniline(CAS: 831-75-4)

3-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS: 831-75-4) is a colorless to pale yellow liquid with a molecular weight of approximately 238.12 g/mol. It has a low solubility in water but is soluble in many organic solvents. The compound is generally stable under normal conditions but reacts with strong oxidizing agents. It exhibits good thermal stability and is used in various applications due to its unique physical and chemical properties.

3-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS: 831-75-4) is commonly synthesized through the reaction of aniline with 1,1,2,2-tetrafluoroethanol in the presence of a suitable catalyst, such as a strong base like sodium hydride. The process involves dehydrating the alcohol to form the corresponding anilide, followed by hydrolysis to introduce the tetrafluoroethoxy group. The overall yield of the reaction is typically around 70-80%.

3-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS: 831-75-4) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It also finds applications in the production of polymers, particularly as a monomer for fluoropolymer synthesis. Additionally, it is used in the development of sensors and as a component in semiconductor manufacturing processes.

When handling 3-(1,1,2,2-Tetrafluoroethoxy)aniline (CAS: 831-75-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Ensure proper storage in a cool, dry place, away from incompatible materials. In case of spillage, neutralize any reactive species and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.