3-Oxetanyl 4-methylbenzenesulfonate(CAS: 26272-83-3)

3-Oxetanyl 4-methylbenzenesulfonate is a crystalline compound with a molecular weight of approximately 241.19 g/mol. It has a solubility of about 2.5 g/L in water at 25°C. Chemically, it is relatively unreactive but can undergo sulfonate displacement reactions. It has a melting point of around 148-150°C.

3-Oxetanyl 4-methylbenzenesulfonate is typically synthesized by the reaction of 4-methylbenzenesulfonyl chloride with 3-oxetanol. The reaction is usually conducted in the presence of a base such as pyridine to enhance the nucleophilicity of 3-oxetanol. The yield is typically around 75-80%, and the product is isolated via recrystallization.

3-Oxetanyl 4-methylbenzenesulfonate is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those that require specific functional groups. It is also utilized in the polymer industry for modifying the properties of polymers, and in the sensor industry for developing chemically sensitive materials.

When handling 3-Oxetanyl 4-methylbenzenesulfonate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled in a fume hood, and the Safety Data Sheet (SDS) should be consulted for further guidance.