(6-Oxo-1,6-dihydro-3-pyridinyl)boronic acid(CAS: 903899-13-8)

(6-Oxo-1,6-dihydro-3-pyridinyl)boronic acid is a white crystalline solid with a molecular weight of approximately 224.11 g/mol. It has a moderate solubility in water and is sparingly soluble in ethanol. Chemically, it is highly reactive, especially under basic conditions, and is used in various organic reactions due to its boronic acid functionality. It exhibits good thermal stability up to 150°C.

(6-Oxo-1,6-dihydro-3-pyridinyl)boronic acid is typically synthesized through a multistep process involving the formation of 3-pyridine boronic acid followed by an oxidation step. This can be achieved using various reagents such as phenylhydrazine, boron tribromide, and hydrogen peroxide. The overall yield is around 75%, and the reaction is conducted under anhydrous conditions to enhance reactivity and yield.

(6-Oxo-1,6-dihydro-3-pyridinyl)boronic acid finds applications in pharmaceuticals, where it serves as a key intermediate in the synthesis of certain drug molecules. It is also utilized in the development of sensors and semiconductors due to its unique functional groups. In the polymer industry, it is used as a cross-linking agent to enhance material properties.

When handling (6-Oxo-1,6-dihydro-3-pyridinyl)boronic acid (CAS: 903899-13-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The substance should always be used in a well-ventilated area or fume hood. Spills should be immediately cleaned up using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed handling and disposal information. This material is reactive and should be stored in a dry, cool place to prevent degradation.