(S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid(CAS: 1217755-81-1)

(S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid is a crystalline solid with a molecular weight of approximately 327.39 g/mol. It has a pKa of around 4.8. The compound is slightly soluble in water and ethanol. It is unstable in acidic conditions and exhibits good reactivity towards nucleophiles.

(S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid can be synthesized using a multistep process involving alkylation of a tert-butoxycarbonyl derivative with 6-methoxy-3-pyridinecarboxaldehyde, followed by reduction and coupling reactions. The yield is typically around 70-80% with high regioselectivity.

(S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds and as a building block in medicinal chemistry. It has potential applications in the polymer and sensor industries as well.

When handling (S)-3-((tert-Butoxycarbonyl)amino)-3-(6-methoxypyridin-3-yl)propanoic acid, wear appropriate personal protective equipment such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place away from direct sunlight and flammable materials. Use a fume hood during any operations involving the compound to minimize exposure. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.