Tetrahydro-2H-pyran-4-amine acetate (1:1)(CAS: 1005498-91-8)

Tetrahydro-2H-pyran-4-amine acetate (CAS: 1005498-91-8) is a white crystalline solid with a molecular weight of approximately 216.24 g/mol. It has a pKa of about 6.2, indicating basicity. The compound is slightly soluble in water and has good solubility in organic solvents such as ethanol and acetone. It is known for its reactivity in nucleophilic substitution reactions and its ability to form stable complexes with various metal ions.

Tetrahydro-2H-pyran-4-amine acetate (CAS: 1005498-91-8) can be synthesized through the acetylation of tetrahydro-2H-pyran-4-amine using acetic anhydride in the presence of a catalytic amount of a strong acid like sulfuric acid. The reaction is typically carried out at room temperature, and the product is purified by recrystallization from aqueous ethanol. This method ensures high yield and good purity of the final product.

Tetrahydro-2H-pyran-4-amine acetate (CAS: 1005498-91-8) is used in the pharmaceutical industry for the synthesis of certain drug intermediates, in the polymer industry for the modification of polymer properties, and in the sensor industry for the development of molecular recognition elements. It also finds applications in the semiconductor industry as a component in surface treatment processes.

When handling Tetrahydro-2H-pyran-4-amine acetate (CAS: 1005498-91-8), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Ensure that the reaction is conducted in a well-ventilated fume hood to avoid inhalation of fumes. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly rinsed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.