4-Bromopyrimidine(CAS: 31462-56-3)

4-Bromopyrimidine (CAS: 31462-56-3) is a crystalline compound with a molecular weight of approximately 167.01 g/mol. It has a melting point of 140-142°C and is slightly soluble in water. It exhibits basic properties and moderate reactivity with nucleophiles. The compound is prone to hydrolysis and can undergo electrophilic aromatic substitution reactions.

4-Bromopyrimidine (CAS: 31462-56-3) is commonly synthesized by bromination of pyrimidine. The process involves treating pyrimidine with bromine in the presence of a suitable solvent such as acetic acid, often with a phase transfer catalyst. The yield is typically around 80%, and the reaction is selective for bromination at the desired position.

4-Bromopyrimidine (CAS: 31462-56-3) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry for the development of new materials, and in sensor technology for detecting specific chemical species.

When handling 4-Bromopyrimidine (CAS: 31462-56-3), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. The substance should be used in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.