3-(1H-Pyrrol-1-yl)benzoic acid(CAS: 61471-45-2)

3-(1H-Pyrrol-1-yl)benzoic acid is a white crystalline solid with a molecular weight of approximately 191.17 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as ethanol and acetone. Chemically, it is an aromatic carboxylic acid and shows moderate reactivity, particularly in esterification and amide formation reactions.

3-(1H-Pyrrol-1-yl)benzoic acid can be synthesized by reacting 1-benzoylpyrrole with a base such as sodium hydroxide or potassium hydroxide. The reaction typically involves heating to promote the formation of the desired acid. This method provides good yield and selectivity, and appropriate catalysts may be used to enhance reactivity.

3-(1H-Pyrrol-1-yl)benzoic acid finds application in pharmaceuticals, where it can be used as a precursor in the synthesis of drug molecules. It is also used in the production of certain sensors and in some polymer formulations due to its ability to form stable esters and amides.

When handling 3-(1H-Pyrrol-1-yl)benzoic acid, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Store the compound in a cool, dry place away from direct sunlight. If a spill occurs, it should be handled using appropriate spill kits or under a fume hood. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.