Methyl 4-acetamido-5-chloro-2-methoxybenzoate(CAS: 4093-31-6)

Methyl 4-acetamido-5-chloro-2-methoxybenzoate is a crystalline compound with a molecular weight of approximately 311.65 g/mol. It has a low solubility in water but is more soluble in organic solvents such as methanol and acetone. The compound is relatively stable under normal conditions but may react with strong bases. It is primarily used in pharmaceutical and polymer synthesis.

Methyl 4-acetamido-5-chloro-2-methoxybenzoate is synthesized through a multi-step process involving the reaction of 2-methoxybenzoic acid with acetamide followed by chlorination. Commonly, this reaction is catalyzed with a Lewis acid and proceeds with high selectivity and yield, making it a cost-effective manufacturing method.

Methyl 4-acetamido-5-chloro-2-methoxybenzoate is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and also finds applications in the development of new polymers with specific properties.

When handling Methyl 4-acetamido-5-chloro-2-methoxybenzoate, it is crucial to use appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a fume hood to minimize inhalation risks. In case of spillage, the area should be cleaned up immediately using appropriate materials, and the Safety Data Sheet (SDS) should be consulted for specific guidelines.