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(3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one(CAS: 356068-93-4)

(3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one
CAS Number

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Basic Information

Molecular Formula
C16H13FN2O3
Molecular Weight
300.29 g/mol

Physical Properties

Boiling Point
588.4°C at 760 mmHg
Density
1.454
Flash Point
309.683 ºC

Chemical Identifiers

SMILES
CC1=C(NC(=C1C(=O)O)C)C=C2C3=C(C=CC(=C3)F)NC2=O
InChIKey
RBHBOUYXUXWCNJ-WDZFZDKYSA-N

Database References

MDL Number
MFCD11521323

FAQ

This compound is a white or off-white crystalline solid at room temperature. Its molecular weight is approximately 363.34 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It is highly reactive towards nucleophiles and exhibits good stability in acidic conditions. The compound is not flammable but may decompose at high temperatures, releasing toxic fumes.
This compound can be synthesized by condensation reactions involving a pyrrole derivative and an indole derivative. The synthesis typically uses a metal catalyst such as copper or palladium. The reaction proceeds with good regioselectivity and yields up to 90%. The reaction conditions should be controlled to avoid side reactions and ensure high purity of the product.
This compound is primarily used in the pharmaceutical industry for the development of novel drugs. It also finds applications in polymer synthesis for developing new materials. Additionally, it is used in the production of sensors and semiconductors due to its unique chemical properties.
When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation of fumes. Spills should be handled using absorbent materials, and the area should be thoroughly cleaned with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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