2-Chloronicotinic acid

Basic Information

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CAS Number

2942-59-8

Molecular Formula

C6H4ClNO2

Molecular Weight

157.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

176-178 °C (dec.)

Boiling Point

316.8°C at 760 mmHg

Density

1.4700

Flash Point

316.8 °C at 760 mmHg

SMILES

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C1=CC(=C(N=C1)Cl)C(=O)O

InChI

InChI=1S/C6H4ClNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H,9,10)

InChIKey

IBRSSZOHCGUTHI-UHFFFAOYSA-N

LogP

1.4332

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

140

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SCHEMBL353141
SMR000221567
M510M47
Q-200263
Niflumic acid impurity A
2-Chloro-nicotinic acid
2-chloropyridine 3-carboxylic acid
PS-5333
InChI=1/C6H4ClNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3H,(H,9,10
AB00651
3-Carboxy-2-chloropyridine
960360-14-9
HY-W017249
BP-11743
FLUNIXIN MEGLUMINE IMPURITY A [EP IMPURITY]
A5493
2-Chloropyridine-3-carboxylic acid
F2191-0179
2-chloro nicotinic acid
AC-907/30003060
FT-0601274
DTXSID9062726
NS00006996
NCGC00246335-01
MLS000332085
chloronicotinic acid
SB40463
2-Chloronicotinicacid
MFCD00006236
AKOS000119897
PD014281

MDL Number

MFCD00006236

Customs Code

2933399010

FAQ

What is 2-Chloronicotinic acid (CAS: 2942-59-8)?

2-Chloronicotinic acid (CAS: 2942-59-8) is a chlorinated derivative of nicotinic acid, with the chemical formula C6H5ClNO2. It is a white crystalline solid, known for its acidity and ability to form salts. Commonly used in chemical synthesis, it exhibits reactivity due to the chlorine substituent on the pyridine ring, making it a key intermediate in pharmaceutical and industrial applications.

What are the main uses of 2-Chloronicotinic acid (CAS: 2942-59-8)?

2-Chloronicotinic acid (CAS: 2942-59-8) is primarily used in pharmaceuticals as a precursor for drug development, including anti-diabetic and anti-inflammatory agents. It also finds applications in the synthesis of pesticides, dyes, and other organic compounds. In research, it serves as a versatile reagent for studying metabolic pathways and developing new materials, leveraging its chemical structure and reactivity.

Is 2-Chloronicotinic acid (CAS: 2942-59-8) safe?

2-Chloronicotinic acid (CAS: 2942-59-8) is generally considered safe when handled properly, but it may have mild toxicity if ingested or inhaled in large quantities. Safety precautions include wearing gloves, goggles, and a lab coat, and ensuring proper ventilation. Adherence to OSHA and EPA guidelines is recommended to minimize risks during storage and use.

How should 2-Chloronicotinic acid (CAS: 2942-59-8) be stored?

2-Chloronicotinic acid (CAS: 2942-59-8) should be stored in a cool, dry place (ideally 2-8°C), protected from light, and in a sealed, airtight container. Maintain low humidity levels to prevent degradation. Avoid exposure to moisture and incompatible substances like strong bases. Keep away from heat sources to ensure stability and prolong shelf life.