How is (3Z)-3-[(3,5-Dimethyl-4-carboxy-1H-pyrrol-2-yl)methylidene]-5-fluoro-1,3-dihydro-2H-indol-2-one (CAS: 356068-93-4) typically synthesized?

This compound can be synthesized by condensation reactions involving a pyrrole derivative and an indole derivative. The synthesis typically uses a metal catalyst such as copper or palladium. The reaction proceeds with good regioselectivity and yields up to 90%. The reaction conditions should be controlled to avoid side reactions and ensure high purity of the product.