N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide(CAS: 918505-84-7)

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide is a crystalline solid with a molecular weight of approximately 461.17 g/mol. It has low water solubility but is soluble in polar organic solvents. The compound is moderately reactive, showing susceptibility to nucleophilic substitution and hydrolysis under certain conditions.

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide is typically synthesized through a multi-step process involving carbonylation, alkylation, and sulfonamidation reactions. The synthesis involves the use of appropriate catalysts and solvents to achieve high selectivity and yield. Specific details of the reaction conditions and reagents are proprietary.

N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide is primarily used in the pharmaceutical industry for its biological activity. It may also find applications in polymer synthesis and as a chemical intermediate in various other industries due to its functional groups and unique molecular structure.

When handling N-(3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a fume hood and use proper ventilation. In case of a spill, neutralize the material with appropriate agents and dispose of according to local regulations. Always consult the safety data sheet (SDS) for detailed handling and disposal instructions.