(1S,2R)-1-Amino-2-indanol(CAS: 7480-35-5)

(1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5) is a crystalline solid with a molecular weight of approximately 146.22 g/mol. It has a solubility of about 0.54 g/100 mL in water and is slightly soluble in ethanol. This compound is reactive, particularly with acidic and basic conditions. It is stable under neutral conditions but requires careful handling due to its sensitivity to moisture and heat.

(1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5) can be synthesized through a multistep process involving the reduction of indanone with sodium borohydride followed by the addition of ammonia. The reaction conditions should be carefully controlled to achieve high selectivity and yield, typically in the presence of a catalytic amount of sodium hydroxide. The final step involves the removal of by-products and purification using recrystallization.

(1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5) is primarily used in the pharmaceutical industry as a precursor in the synthesis of various bioactive molecules. It also finds applications in the polymer industry for the development of new materials with specific functional groups. Additionally, it is utilized in the production of sensors and semiconductors due to its unique reactivity and solubility properties.

When handling (1S,2R)-1-Amino-2-indanol (CAS: 7480-35-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions and ensure proper storage in a cool, dry area away from direct sunlight and heat sources.