7-Nitro-1H-indole-2,3-dione(CAS: 112656-95-8)

7-Nitro-1H-indole-2,3-dione is a crystalline compound with a molecular weight of approximately 228.11 g/mol. It has a solubility of about 0.1 g/L in water. The compound is moderately reactive, particularly towards reducing agents and bases. It is stable under standard storage conditions but should be handled with care to avoid decomposition.

7-Nitro-1H-indole-2,3-dione can be synthesized via the nitration of indole-2,3-dione. Common methods involve the use of nitric acid and sulfuric acid as the nitrating agent. The reaction is typically carried out in a solvent like glacial acetic acid, yielding a product with a high degree of purity and selectivity.

7-Nitro-1H-indole-2,3-dione is primarily used in the pharmaceutical industry for the synthesis of various biologically active compounds. It is also utilized in the production of certain dyes and pigments due to its aromatic structure. Additionally, it has applications in the development of sensors and as an intermediate in the production of certain semiconductors.

When handling 7-Nitro-1H-indole-2,3-dione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood to avoid inhalation of fumes. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.