1-(Aminomethyl)cyclobutanol(CAS: 180205-28-1)

1-(Aminomethyl)cyclobutanol (CAS: 180205-28-1) is a colorless liquid with a pungent odor. It has a molecular weight of approximately 104.13 g/mol and a boiling point of 177°C. This compound is moderately soluble in water and organic solvents. It is reactive towards nucleophiles and can undergo substitution reactions. It is generally stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

1-(Aminomethyl)cyclobutanol can be synthesized via a multi-step process involving the condensation of cyclobutanone with ammonia followed by reduction. Commonly used catalysts include palladium on carbon. The synthetic route typically achieves a yield of around 70-80%, with good selectivity and purity. This reaction should be conducted under nitrogen to prevent oxidation.

1-(Aminomethyl)cyclobutanol (CAS: 180205-28-1) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also applied in the polymer industry as a monomer for the production of special polymers with unique properties. Additionally, it is utilized in the semiconductor industry for the fabrication of sensors and in the sensor industry for developing gas detection devices.

When handling 1-(Aminomethyl)cyclobutanol (CAS: 180205-28-1), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Laboratory work involving this compound should be conducted in a well-ventilated area or a fume hood. Spills should be handled immediately by sweeping into a container and disposing of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage.