N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide(CAS: 1191911-27-9)

N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide is a crystalline compound with a molecular weight of approximately 562.9 g/mol. It has a high solubility in organic solvents like dimethylformamide and methanol. The compound is known for its low reactivity under standard laboratory conditions, with minimal tendency to undergo hydrolysis or oxidation. This stability makes it suitable for long-term storage and handling in various applications.

N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide is synthesized through a multi-step process involving the coupling of 5-chloro-2-aminopyrimidine and 2-methoxy-4-(4-morpholinyl)phenylamine. The reaction is typically carried out in the presence of a suitable catalyst, such as 4-(dimethylamino)pyridine (DMAP), and a base like triethylamine (TEA). The yield is generally high, and the product can be obtained with good purity.

N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide is used in pharmaceuticals for its potential therapeutic applications, particularly in the development of antiviral and anticancer drugs. It is also utilized in the semiconductor industry for its unique electronic properties and in the production of sensors due to its stable and reproducible behavior.

When handling N-{2-[(5-Chloro-2-{[2-methoxy-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)amino]phenyl}methanesulfonamide (CAS: 1191911-27-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. In case of a spill, it should be cleaned up carefully using appropriate absorbent materials, and the area should be thoroughly washed. For detailed safety information, refer to the Safety Data Sheet (SDS) for the compound.