2-(6-Chloropyrazin-2-yl)acetic acid(CAS: 930798-25-7)

2-(6-Chloropyrazin-2-yl)acetic acid (CAS: 930798-25-7) is a white crystalline solid with a molecular weight of approximately 225.02 g/mol. It is poorly water-soluble, with a solubility of less than 1 g/L at 25°C. The compound exhibits acidity and can undergo substitution reactions due to the presence of the chloro and carboxylic acid functionalities.

2-(6-Chloropyrazin-2-yl)acetic acid is typically synthesized via the reaction of 6-chloropyrazine-2-carbaldehyde with acetylene followed by hydrolysis. The synthesis involves the use of palladium catalysts for the alkylation step, ensuring high selectivity and yield. Detailed reaction conditions and safety precautions are outlined in the literature.

2-(6-Chloropyrazin-2-yl)acetic acid (CAS: 930798-25-7) is primarily used in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients (APIs). It also finds applications in the development of sensors and as a precursor in the synthesis of other organic compounds.

When handling 2-(6-Chloropyrazin-2-yl)acetic acid (CAS: 930798-25-7), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up using appropriate absorbent materials, and disposal should be done in accordance with local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.