Compound Q&A

How is 2-(6-Chloropyrazin-2-yl)acetic acid (CAS: 930798-25-7) typically synthesized?

Answer

2-(6-Chloropyrazin-2-yl)acetic acid
2-(6-Chloropyrazin-2-yl)acetic acid is typically synthesized via the reaction of 6-chloropyrazine-2-carbaldehyde with acetylene followed by hydrolysis. The synthesis involves the use of palladium catalysts for the alkylation step, ensuring high selectivity and yield. Detailed reaction conditions and safety precautions are outlined in the literature.

About

English Name 2-(6-Chloropyrazin-2-yl)acetic acid
Molecular Formula C6H5ClN2O2
Molecular Weight 172.57 g/mol
SMILES C1=C(N=C(C=N1)Cl)CC(=O)O
InChIKey GKCGKFUOTLQOGO-UHFFFAOYSA-N
Last Updated: 2025-11-01 18:55

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