(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid(CAS: 186023-49-4)

(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid is a white crystalline solid with a molecular weight of approximately 513.4 g/mol. It has low water solubility and high solubility in organic solvents. The compound is known for its reactivity in peptide coupling reactions and can form stable esters and amides. It is stable under normal storage conditions but should be protected from moisture and heat.

(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid is usually synthesized via the coupling of fluoren-9-ylmethanol with L-valine using a suitable coupling reagent such as HATU or DCC in the presence of a base like DIPEA. The reaction proceeds via a Michael addition followed by a coupling step to form the desired product.

(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid is primarily used in the pharmaceutical industry for the synthesis of peptide-based drugs. It is also utilized in the production of certain types of polymers and as a building block for custom organic synthesis in academic and industrial research settings.

When handling (4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and laboratory coat. The substance should be handled in a well-ventilated area or a fume hood. In case of a spill, follow the manufacturer's safety data sheet (SDS) guidelines for cleanup. This compound is not highly reactive but should be protected from moisture and heat to maintain stability.