Compound Q&A
How is (4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid (CAS: 186023-49-4) typically synthesized?
Answer
![(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid](https://static.chemtradehub.com/structs/186/186023-49-4-386c.webp "(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid")
(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid is usually synthesized via the coupling of fluoren-9-ylmethanol with L-valine using a suitable coupling reagent such as HATU or DCC in the presence of a base like DIPEA. The reaction proceeds via a Michael addition followed by a coupling step to form the desired product.
About
CAS No
186023-49-4
English Name
(4S)-3-{N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl}-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
Molecular Formula
C26H30N2O6
Molecular Weight
466.53 g/mol
SMILES
CC(C)[C@@H](C(=O)N1[C@@H](COC1(C)C)C(=O)O)NC(=O)OCC2c3ccccc3-c4c2cccc4
InChIKey
KLYUTTJBDDHKOC-VXKWHMMOSA-N
Last Updated: 2025-11-08 00:00
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