5-(Aminomethyl)-3-pyridinamine(CAS: 754129-80-1)

5-(Aminomethyl)-3-pyridinamine is a crystalline solid with a molecular weight of approximately 133.12 g/mol. It has a solubility of around 20 mg/mL in water and is slightly soluble in common organic solvents. This compound is generally stable under normal conditions but can react with strong acids and bases. It has been used in various synthesis reactions due to its amine functionality.

5-(Aminomethyl)-3-pyridinamine can be synthesized through the reaction of 3-pyridylamine with methyl acetylene-polymerized diene (MAPD). The reaction involves the dehydrogenation of 3-pyridylamine to form the target product. Commonly, this synthesis is conducted under basic conditions to enhance the reaction's efficiency and yield.

5-(Aminomethyl)-3-pyridinamine is primarily used in the pharmaceutical industry due to its amine functionality, which allows for the modification of various drug molecules. It is also used in the synthesis of certain polymers and as a precursor in semiconductor manufacturing for its unique electronic properties.

When handling 5-(Aminomethyl)-3-pyridinamine, wear appropriate protective equipment such as gloves and goggles. It should be stored in a cool, dry place away from strong acids and bases. In case of spills, use appropriate PPE and clean up with a suitable absorbent material. Always refer to the Safety Data Sheet (SDS) for detailed instructions and emergency procedures.