2-(Bromomethyl)-3-chlorobenzonitrile(CAS: 77533-18-7)

2-(Bromomethyl)-3-chlorobenzonitrile (CAS: 77533-18-7) is a crystalline solid with a molecular weight of approximately 248.01 g/mol. It has a low water solubility but is soluble in common organic solvents like dichloromethane and acetone. The compound is moderately reactive, especially towards nucleophiles, and exhibits亲电性 towards electrophiles. It is stable under normal conditions but requires handling with care due to its halogen-containing nature.

2-(Bromomethyl)-3-chlorobenzonitrile (CAS: 77533-18-7) can be synthesized via the reaction of 3-chlorobenzonitrile with bromomethyl ketone. This process typically involves heating the reactants in the presence of a catalyst such as a Lewis acid. The reaction is selective and yields a high purity product with good yield under appropriate reaction conditions.

2-(Bromomethyl)-3-chlorobenzonitrile (CAS: 77533-18-7) is used in various industries, including pharmaceuticals for the synthesis of certain pharmaceutical intermediates, and in the production of materials for sensors and semiconductors. It is also utilized in polymer research for developing novel materials with specific properties.

When handling 2-(Bromomethyl)-3-chlorobenzonitrile (CAS: 77533-18-7), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat to prevent skin and eye contact. The compound should be stored in a closed container, away from heat and direct sunlight. In case of a spill, it should be handled with appropriate cleanup procedures, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed handling and emergency procedures.