4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane(CAS: 269410-26-6)

4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane is a colorless to white crystalline solid with a molecular weight of approximately 332.3 g/mol. It is moderately soluble in common organic solvents like DMF and THF. The compound shows good reactivity in boron-containing reactions, such as cross-coupling reactions. It is stable under normal conditions but should be stored away from moisture and heat.

4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane is typically synthesized via a Grignard reaction. The process involves the reaction of 4-phenoxyphenylmagnesium bromide with tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborane in a dry, anhydrous solvent. The reaction conditions include the use of a catalytic amount of a base like triethylamine to enhance the reaction yield and selectivity.

4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane is used in the pharmaceutical industry for the synthesis of complex organic molecules and in the semiconductor industry for the preparation of boron-containing materials. It is also applied in the field of sensor technology for the development of novel gas sensors.

When handling 4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane, appropriate personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a lab coat. The compound should be stored in a cool, dry place away from moisture. If a spill occurs, it should be cleaned up using appropriate methods, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.