(2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester(CAS: 68195-02-8)

(2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester (CAS: 68195-02-8) is a crystalline solid with a molecular weight of approximately 268.27 g/mol. It has a pKa of 4.3 and is moderately soluble in water. This compound is known for its reactive nature, particularly towards nucleophiles and bases.

(2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester (CAS: 68195-02-8) is synthesized by the esterification of 2-amino-benzothiazol-6-yl-acetic acid with ethanol in the presence of a catalytic amount of acid. Commonly, this is achieved using sulfuric acid or p-toluenesulfonic acid as the catalyst. The reaction is carried out at room temperature to moderate heat, yielding a high selectivity and good yield.

(2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester (CAS: 68195-02-8) has applications in the pharmaceutical industry for its role as a precursor in the synthesis of bioactive compounds. It is also used in the polymer industry for its stabilizing properties and in the development of sensors for detecting specific analytes.

When handling (2-Amino-benzothiazol-6-yl)-acetic acid ethyl ester (CAS: 68195-02-8), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Always use a fume hood to minimize exposure to fumes. Proper storage in a cool, dry place away from heat and oxidizers is crucial. In case of spill, clean up using appropriate methods and refer to the Safety Data Sheet (SDS) for detailed instructions.