Methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate(CAS: 81569-46-2)

Methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate (CAS: 81569-46-2) is a crystalline solid with a molecular weight of approximately 255.03 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophiles and thiols. It decomposes above 180°C.

Methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate (CAS: 81569-46-2) is synthesized by the reaction of methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate with bromine followed by workup. The reaction is catalyzed by a suitable base, and the product is isolated by recrystallization. The yield is typically 75-80%.

Methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate (CAS: 81569-46-2) is used primarily in the pharmaceutical industry for the synthesis of various biologically active compounds. It is also used in the production of certain types of polymers and as a precursor in the development of sensors and semiconductors.

When handling Methyl 2-bromo-5-ethyl-1,3-thiazole-4-carboxylate (CAS: 81569-46-2), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed with water. Always refer to the Safety Data Sheet (SDS) for detailed safety information.