5-Amino-2-benzofuran-1(3H)-one(CAS: 65399-05-5)

5-Amino-2-benzofuran-1(3H)-one (CAS: 65399-05-5) is a crystalline solid with a molecular weight of approximately 210.23 g/mol. It has a solubility of about 0.17 g/L in water. This compound is relatively stable, but it reacts with strong acids and bases. It is slightly soluble in ethanol and soluble in chloroform and dichloromethane.

5-Amino-2-benzofuran-1(3H)-one is typically synthesized via a multistep process involving the condensation of an appropriate aldehyde with 2-furylamine, followed by cyclization. This process often utilizes mild acid catalysis and produces the desired compound with moderate to good yield.

5-Amino-2-benzofuran-1(3H)-one (CAS: 65399-05-5) is used in various industries, particularly in pharmaceuticals for its potential as a drug intermediate. It also finds application in polymer chemistry for the synthesis of certain polymers and in the development of sensors and semiconductors.

When handling 5-Amino-2-benzofuran-1(3H)-one (CAS: 65399-05-5), it is important to wear appropriate personal protective equipment (PPE), including gloves and lab coat, to protect against skin contact and inhalation. Handle this compound under a fume hood to minimize exposure. In case of a spill, immediately clean up using appropriate procedures and refer to the safety data sheet (SDS) for detailed instructions.