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N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide(CAS: 918504-27-5)

N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide
CAS Number

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Basic Information

Molecular Formula
C17H14BrF2N3O3S
Molecular Weight
458.28 g/mol

Physical Properties

Boiling Point
634.2°C at 760 mmHg

Chemical Identifiers

SMILES
CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)Br)F
InChIKey
TVFGCDQPUZGXMQ-UHFFFAOYSA-N

Database References

MDL Number
MFCD18207768

FAQ

N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS: 918504-27-5) is a crystalline compound with a molecular weight of approximately 492.08 g/mol. It has low water solubility. The compound is reactive and can form complexes with various metals. It is stable under normal conditions but should be stored in a dry, cool, and well-ventilated area to prevent degradation.
N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS: 918504-27-5) can be synthesized through a multi-step process involving the coupling of 2,4-difluorophenyl propionyl chloride with 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl chloride, followed by the condensation of the resulting intermediate with propane-1-sulfonic acid. This process yields the target compound with high selectivity and good yield.
N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS: 918504-27-5) is primarily used in the pharmaceutical industry for its potential as a drug candidate. It is also of interest in the sensor technology and semiconductor industries due to its unique chemical properties.
When handling N-(3-(5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide (CAS: 918504-27-5), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be handled in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate spill kits, and the area should be thoroughly ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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