Methyl O-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serinate(CAS: 134167-07-0)

Methyl O-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serinate is a crystalline compound with a molecular weight of approximately 311.34 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is reactive towards nucleophiles and can undergo esterification and hydrolysis reactions. It typically forms crystalline solids with a melting point around 180-185°C.

Methyl O-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serinate can be synthesized through a multi-step process involving esterification and amidation reactions. The synthesis typically uses L-serine as the starting material, followed by methylation and esterification steps. Commonly, a catalyst such as an acid (e.g., acetic acid) or base (e.g., sodium hydroxide) is used to enhance the reaction selectivity and yield, which can be up to 80% under optimized conditions.

Methyl O-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serinate finds applications in the pharmaceutical industry for the synthesis of intermediates and drug candidates. It is also used in the polymer industry as a monomer for specific polymer formulations. Additionally, it can be used in the development of sensors and semiconductors due to its functional groups and reactivity.

When handling Methyl O-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serinate (CAS: 134167-07-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbents and neutralizing agents. Ensure proper storage in a cool, dry place, away from strong acids, bases, and oxidizers. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.