Methyl 5-nitro-2-(1-piperazinyl)benzoate(CAS: 886360-73-2)

Methyl 5-nitro-2-(1-piperazinyl)benzoate (CAS: 886360-73-2) is a crystalline solid with a molecular weight of approximately 296.16 g/mol. It has a solubility of about 1.5 g/L in water and is slightly soluble in ethanol. The compound is moderately reactive towards acids and bases. It is stable under standard storage conditions but should be protected from moisture and light.

Methyl 5-nitro-2-(1-piperazinyl)benzoate is typically synthesized through a multi-step process involving the condensation of 2-nitrobenzoic acid with piperazine followed by methylation. Common solvents used include acetic anhydride, and the reaction is often catalyzed by concentrated sulfuric acid. The yield is generally around 70-80%, with high selectivity for the desired product.

Methyl 5-nitro-2-(1-piperazinyl)benzoate (CAS: 886360-73-2) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various medicinal compounds. It is also utilized in the development of sensors and materials for electronic applications.

When handling Methyl 5-nitro-2-(1-piperazinyl)benzoate (CAS: 886360-73-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and chemical-resistant lab coats. The substance should be handled in a well-ventilated area, preferably under a fume hood. Spills should be immediately neutralized with an appropriate chemical neutralizer and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.