2-(4-Morpholinylmethyl)benzoic acid(CAS: 868543-19-5)

2-(4-Morpholinylmethyl)benzoic acid (CAS: 868543-19-5) has a crystalline form with a molecular weight of approximately 256.41 g/mol. It is slightly soluble in water and soluble in organic solvents like ethanol and acetonitrile. The compound is reactive, especially under basic conditions, and can form salts and esters. It has a pKa value of about 4.5, indicating its acidity in aqueous solutions.

2-(4-Morpholinylmethyl)benzoic acid (CAS: 868543-19-5) is typically synthesized by reacting 4-(morpholinomethyl)benzaldehyde with hydroxylamine hydrochloride in a basic medium. The reaction involves condensation and subsequent hydrolysis, yielding the target compound with good yield and selectivity. Common solvents include methanol and ethanol, and the use of a catalyst like sodium hydroxide enhances the reaction rate and product purity.

2-(4-Morpholinylmethyl)benzoic acid (CAS: 868543-19-5) is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for modifying the properties of polymers, and in the sensor industry for developing more sensitive detection methods. Additionally, it is used in the semiconductor industry for etching and cleaning processes due to its acidic nature.

When handling 2-(4-Morpholinylmethyl)benzoic acid (CAS: 868543-19-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure to airborne particles. In case of a spill, it should be cleaned up with appropriate tools and materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.