4-(Benzyloxy)-1H-indole-3-carbaldehyde(CAS: 7042-71-9)

4-(Benzyloxy)-1H-indole-3-carbaldehyde is a white crystalline solid with a molecular weight of approximately 282.25 g/mol. It is sparingly soluble in water but more soluble in organic solvents like ethanol and dichloromethane. This compound is prone to oxidation and exhibits moderate reactivity under basic conditions. It is a valuable intermediate in organic synthesis.

4-(Benzyloxy)-1H-indole-3-carbaldehyde is typically synthesized via a multi-step process starting from indole. The key steps include protection of the indole with a benzyloxycarbonyl group, followed by an oxidation reaction to introduce the aldehyde functionality. This process is carried out under controlled conditions to ensure high yield and selectivity.

4-(Benzyloxy)-1H-indole-3-carbaldehyde (CAS: 7042-71-9) is primarily used in the pharmaceutical industry as a precursor for the synthesis of various biologically active compounds. It also finds applications in the production of certain dyes and as a key intermediate in the synthesis of materials for sensors and semiconductors.

When handling 4-(Benzyloxy)-1H-indole-3-carbaldehyde, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the safety data sheet (SDS) for detailed handling and disposal information.