1-(3-Aminopropyl)-2-pyrrolidinone(CAS: 7663-77-6)

1-(3-Aminopropyl)-2-pyrrolidinone (CAS: 7663-77-6) is a colorless to pale yellow liquid with a molecular weight of approximately 146.24 g/mol. It has a pKa of around 9.5. The compound is slightly soluble in water and miscible with ethanol and ether. It is chemically stable but can undergo hydrolysis in the presence of strong acids or bases. It is also known for its ability to form coordination complexes with metal ions.

1-(3-Aminopropyl)-2-pyrrolidinone is typically synthesized by reacting 3-aminopropylamine with pyrrolidone in the presence of an appropriate catalyst such as a Lewis acid. The reaction is exothermic and requires careful monitoring. The yield is usually around 90%, and the product can be purified by distillation or recrystallization.

1-(3-Aminopropyl)-2-pyrrolidinone (CAS: 7663-77-6) is used in various industrial applications including pharmaceuticals, where it serves as a solubilizing agent for poorly water-soluble drugs; in polymers, where it acts as a plasticizer; in sensors, as a reagent for detecting metal ions; and in semiconductor manufacturing, as a surfactant in cleaning processes.

When handling 1-(3-Aminopropyl)-2-pyrrolidinone (CAS: 7663-77-6), it is important to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. Work should be carried out in a well-ventilated area or a fume hood. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.