Fosfluconazole(CAS: 194798-83-9)

Fosfluconazole (CAS: 194798-83-9) is a crystalline compound with a molecular weight of approximately 410.56 g/mol. It has a low solubility in water (0.02 g/L at 25°C) and is more soluble in organic solvents like methanol and ethanol. Fosfluconazole is moderately reactive with strong bases and is stable under normal conditions but can degrade under acidic or oxidative conditions.

Fosfluconazole (CAS: 194798-83-9) is typically synthesized through a multi-step process involving amidation and cyclization reactions. The synthesis begins with the transformation of a fluconazole derivative into a key intermediate, followed by amidation with 2-fluorobenzylamine. The final product is obtained through a cyclization step. Common catalysts include triphenylphosphine and other organophosphorus compounds, with yields typically ranging from 60% to 70%.

Fosfluconazole (CAS: 194798-83-9) is primarily used in the pharmaceutical industry as an antifungal agent. It is also utilized in the agricultural sector as a fungicide. Additionally, due to its chemical structure, it may have applications in the development of certain sensors and materials science research.

When handling Fosfluconazole (CAS: 194798-83-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood due to its potential for volatility and reactivity. Spills should be cleaned up with caution, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed emergency procedures and handling guidelines.