Azacitidine Impurity 11(CAS: 16352-06-0)

Azacitidine Impurity 11 (CAS: 16352-06-0) is a crystalline compound with a molecular weight of approximately 183.17 g/mol. It is sparingly soluble in water and ethanol. This impurity exhibits low reactivity under normal conditions, making it stable under various environmental and storage conditions. It is used in pharmaceutical research and development, particularly in the synthesis of nucleoside analogs.

Azacitidine Impurity 11 (CAS: 16352-06-0) is synthesized through a multi-step organic reaction process. The synthesis typically involves the condensation of a specific carbamoyl chloride with a nucleoside derivative. The process requires the use of a Lewis acid catalyst, such as aluminum chloride, to promote the reaction. High selectivity and yield are achieved under controlled conditions in a fume hood.

Azacitidine Impurity 11 (CAS: 16352-06-0) is primarily used in the pharmaceutical industry for the development and production of anti-cancer drugs. It is also utilized in research laboratories for the study of nucleoside analogs and their applications in targeted therapies.

When handling Azacitidine Impurity 11 (CAS: 16352-06-0), it is recommended to wear appropriate personal protective equipment (PPE), including gloves, laboratory coat, and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, avoid direct contact and neutralize with an appropriate chemical before cleaning up. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.