H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH(CAS: 115044-69-4)

H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH (CAS: 115044-69-4) is a cyclic heptapeptide with a molecular weight of approximately 958 Da. It crystallizes in a rhombohedral form and is soluble in water. This compound exhibits moderate reactivity, particularly towards nucleophilic attack and amide bond formation. It is stable under neutral and slightly acidic conditions but can degrade under strongly acidic or basic conditions.

H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH (CAS: 115044-69-4) is synthesized through solid-phase peptide synthesis (SPPS). Commonly, the Fmoc (fluorenylmethyl carbamate) method is used, with Fmoc-amino acids and HATU (O-(7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate) as a coupling reagent. The peptide is then deprotected, purified by HPLC, and characterized by mass spectrometry.

H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH (CAS: 115044-69-4) is primarily used in the pharmaceutical industry for its potential as a drug candidate. It also finds applications in biotechnology and research, particularly in the development of immunological and bioassay reagents. This cyclic heptapeptide is less commonly used in industries such as polymers, sensors, and semiconductors.

When handling H-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH (CAS: 115044-69-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. This compound should be stored in a closed container at a cool, dry place and away from light. Spills should be handled with care using absorbent materials, followed by thorough cleaning with water and neutralization, if necessary. Always refer to the safety data sheet (SDS) for detailed handling procedures and emergency response information.