Hexyl 5-amino-4-oxopentanoate hydrochloride (1:1)(CAS: 140898-91-5)

Hexyl 5-amino-4-oxopentanoate hydrochloride (CAS: 140898-91-5) is a white crystalline solid with a molecular weight of approximately 261.35 g/mol. It has a pKa of about 2.3 and is slightly soluble in water. It is more soluble in organic solvents like ethanol and acetone. The compound is reactive due to the presence of the amino and carboxylic acid groups, which can participate in condensation and substitution reactions.

Hexyl 5-amino-4-oxopentanoate hydrochloride (CAS: 140898-91-5) can be synthesized by reacting hexanoyl chloride with 5-amino-4-oxopentanoic acid. The reaction is typically carried out in the presence of a catalyst such as 4-(dimethylamino)pyridine (DMAP) to enhance the reactivity. The yield is generally around 80-85%, and the product is purified by recrystallization from ethanol.

Hexyl 5-amino-4-oxopentanoate hydrochloride (CAS: 140898-91-5) is primarily used in the pharmaceutical industry for the synthesis of certain active pharmaceutical ingredients (APIs) due to its amine and carboxylic acid functionalities. It can also be utilized in the polymer industry as a functional monomer. Additionally, it has applications in the development of sensors and as a precursor in semiconductor manufacturing.

When handling Hexyl 5-amino-4-oxopentanoate hydrochloride (CAS: 140898-91-5), safety precautions should include wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed information and emergency procedures.