ethyl 4-amino-3-methylbenzoate(CAS: 40800-65-5)

Ethyl 4-amino-3-methylbenzoate is a crystalline compound with a molecular weight of approximately 197.23 g/mol. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone. Chemically, it is less reactive but can undergo substitution reactions. The compound has a pKa of around 10.5, indicating basic properties due to the amino group.

Ethyl 4-amino-3-methylbenzoate is typically synthesized from 4-amino-3-methylbenzoic acid and ethyl bromide in the presence of a base like sodium hydride. The reaction involves nucleophilic substitution, yielding the desired product with good yield. This method ensures high selectivity and purity of the final compound.

Ethyl 4-amino-3-methylbenzoate is used in various industries, including pharmaceuticals for intermediate production, and dye-making for colorants in textiles. It also finds applications in polymer-based coatings and as a sensor component in chemical sensors.

Precautions when handling ethyl 4-amino-3-methylbenzoate include using personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, neutralize the acid with a base, and dispose of it according to local regulations. Always consult the safety data sheet (SDS) for detailed handling procedures.