(1-Methyl-1H-pyrazol-4-yl)methanol(CAS: 112029-98-8)

(1-Methyl-1H-pyrazol-4-yl)methanol is a white to off-white crystalline solid with a molecular weight of approximately 141.17 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and methanol. It is moderately reactive, showing basic properties due to the presence of the pyrazole ring. It can undergo nucleophilic substitution and condensation reactions, making it useful in organic synthesis.

(1-Methyl-1H-pyrazol-4-yl)methanol can be synthesized by the reduction of 1-methyl-1H-pyrazole-4-carbaldehyde with sodium borohydride. This method provides good yield and high selectivity. The reaction is typically performed in an alcohol solvent like methanol or ethanol under basic conditions. The use of a suitable catalyst may improve the reaction efficiency.

(1-Methyl-1H-pyrazol-4-yl)methanol is used in the pharmaceutical industry for the synthesis of various heterocyclic compounds that are important for drug development. It is also utilized in polymer chemistry for the creation of functional polymers. Additionally, it has applications in sensor technology and semiconductor manufacturing due to its reactivity and functionality.

When handling (1-Methyl-1H-pyrazol-4-yl)methanol, appropriate personal protective equipment (PPE) should be worn, including gloves, safety goggles, and lab coat. The substance should be stored in a cool, dry, and well-ventilated area away from direct sunlight and heat sources. Fume hoods should be used during preparation and manipulation. In case of a spill, immediately clean up the area using appropriate safety measures and refer to the Safety Data Sheet (SDS) for detailed instructions.