7-Chloro-5-(methylsulfanyl)imidazo[1,2-c]pyrimidine(CAS: 872059-27-3)

7-Chloro-5-(methylsulfanyl)imidazo[1,2-c]pyrimidine is a solid with a crystalline form. Its molecular weight is approximately 213.02 g/mol. It has low water solubility but good solubility in organic solvents. This compound is moderately reactive, particularly towards nucleophiles. It is stable under normal laboratory conditions but should be handled with care to avoid decomposition.

7-Chloro-5-(methylsulfanyl)imidazo[1,2-c]pyrimidine can be synthesized through a multi-step process involving the condensation of 5-methylsulfanylimidazole-1-carbaldehyde with chloroacetic acid. The reaction proceeds under mild conditions using catalysis by a transition metal complex. This method ensures high selectivity and yield, typically around 85-90%.

7-Chloro-5-(methylsulfanyl)imidazo[1,2-c]pyrimidine is primarily used in the pharmaceutical industry for its biological activity. It has shown potential as an antifungal agent. Additionally, it may have applications in the polymer industry as a functional monomer, although its use in this field is less common compared to pharmaceutical applications.

Proper personal protective equipment (PPE) should be worn when handling 7-Chloro-5-(methylsulfanyl)imidazo[1,2-c]pyrimidine, including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.