N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine(CAS: 61747-22-6)

N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine is a crystalline solid with a molecular weight of approximately 364.9 g/mol. It has a low solubility in water but is more soluble in organic solvents such as dichloromethane and acetonitrile. This compound exhibits moderate reactivity, particularly towards nucleophiles and electrophiles, making it useful in organic synthesis. It is stable under normal storage conditions but should be stored in a cool, dark place to preserve its properties.

N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine is typically synthesized through a multi-step process involving the condensation of a trifluoromethylated aryl amine with an appropriate acid chloride in the presence of a suitable base. The synthesis often requires the use of catalytic amounts of a Lewis acid to promote the reaction. The yield is generally good, with selectivity towards the desired product, making it a valuable intermediate in organic chemistry.

N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine is used primarily in the pharmaceutical industry for the synthesis of新型药物中间体，以及在聚合物和传感器领域作为功能性单体和传感材料。此外，它还在半导体制造中作为掺杂剂，用于提高材料性能。

When handling N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dark place to avoid degradation. In the event of a spill, it should be cleaned up according to the Material Safety Data Sheet (MSDS) guidelines, and the area should be ventilated. Fume hoods should be used during synthesis to minimize exposure. It is also recommended to consult the SDS for more detailed safety information.