Compound Q&A

How is N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine (CAS: 61747-22-6) typically synthesized?

Answer

N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine
N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine is typically synthesized through a multi-step process involving the condensation of a trifluoromethylated aryl amine with an appropriate acid chloride in the presence of a suitable base. The synthesis often requires the use of catalytic amounts of a Lewis acid to promote the reaction. The yield is generally good, with selectivity towards the desired product, making it a valuable intermediate in organic chemistry.

About

CAS No 61747-22-6
English Name N-Hydroxy-5-methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanimine
Molecular Formula C13H16F3NO2
Molecular Weight 275.27 g/mol
SMILES COCCCCC(=NO)C1=CC=C(C=C1)C(F)(F)F
InChIKey UDCRPPVSQRFBKJ-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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