4-Amino-3-methylbenzonitrile(CAS: 78881-21-7)

4-Amino-3-methylbenzonitrile is a white crystalline solid with a molecular weight of 155.16 g/mol. It is slightly soluble in water and more soluble in organic solvents like acetone and ethanol. Chemically, it is reactive towards electrophiles and can participate in substitution reactions.

4-Amino-3-methylbenzonitrile is typically synthesized by the reaction of 3-methylbenzoyl chloride with ammonia. This process involves the substitution of a chlorine atom with an amino group, yielding the desired product with high selectivity and yield.

4-Amino-3-methylbenzonitrile is used in the pharmaceutical industry as an intermediate in the synthesis of various drug candidates. It also finds applications in the polymer industry for the production of certain types of resins and in the sensor industry for developing gas detection devices.

When handling 4-Amino-3-methylbenzonitrile, use personal protective equipment like gloves, goggles, and lab coats. Store it in a cool, well-ventilated area, away from heat sources. In case of spills, use appropriate absorbent materials and dispose of them according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling instructions.