Ethyl 6-quinolinecarboxylate(CAS: 73987-38-9)

Ethyl 6-quinolinecarboxylate (CAS: 73987-38-9) is a yellow crystalline solid with a molecular weight of approximately 223.22 g/mol. It has a solubility of 0.15 g/100 mL in water and is soluble in common organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but can undergo hydrolysis in the presence of strong acids or bases. It is not highly reactive but should be handled in a fume hood to minimize exposure.

Ethyl 6-quinolinecarboxylate (CAS: 73987-38-9) is typically synthesized via the reaction of 6-quinolinol with ethyl chloroformate in the presence of a base like potassium carbonate. The reaction is carried out in a solvent such as dimethylformamide (DMF) at room temperature. The yield is usually around 85-90%, and the product is purified by recrystallization from ethanol.

Ethyl 6-quinolinecarboxylate (CAS: 73987-38-9) is used in the pharmaceutical industry as a precursor for the synthesis of certain quinoline-based drugs. It is also utilized in the polymer industry for the production of functionalized polymers with improved properties. Additionally, it can be employed in the development of sensors and semiconductors due to its unique chemical properties.

When handling Ethyl 6-quinolinecarboxylate (CAS: 73987-38-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or fume hood due to its potential to release harmful vapors. In case of a spill, immediately clean up using absorbent materials and dispose of them according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.