1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-1H-imidazole(CAS: 1351478-35-7)

The compound has a crystalline form with a molecular weight of approximately 418.47 g/mol. It is slightly soluble in water and organic solvents such as methanol and acetonitrile. Its reactivity is moderate, showing mild nucleophilic substitution in the presence of appropriate catalysts. It is stable under normal conditions but can degrade under acidic or basic conditions.

This compound is typically synthesized via a Suzuki coupling reaction between 4-bromobenzylamine and tetramethyl-1,3,2-dioxaborolane in the presence of palladium(II) acetate and a ligand. The yield is around 70-80% with good regioselectivity. The reaction is typically performed under microwave-assisted conditions to enhance reactivity and yield.

This compound is used in pharmaceuticals for its potential as a drug candidate, particularly in antimicrobial and antiviral applications. It is also utilized in the preparation of polymers and sensors due to its structural features. Additionally, it can be employed in semiconductor applications for its electronic properties.

Handling this compound requires the use of personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a fume hood to minimize exposure. In case of a spill, it is recommended to clean up with caution, using appropriate absorbent materials, and disposing of the waste according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed guidance on handling and storage.