Ethyl 3-phenylpropanoate(CAS: 2021-28-5)

Ethyl 3-phenylpropanoate (CAS: 2021-28-5) is a colorless to light yellow liquid with a molecular weight of approximately 184.26 g/mol. It has a high solubility in organic solvents but is practically insoluble in water. Chemically, it is relatively stable but can react with strong nucleophiles. It has a melting point of -25°C and a boiling point of 138-139°C. This compound is also known for its pleasant aroma, making it useful in fragrances.

Ethyl 3-phenylpropanoate can be synthesized via an esterification reaction between phenylpropanol and ethyl acetate. Commonly, this reaction is catalyzed by sulfuric acid under reflux conditions. The process involves heating the mixture until the esterification is complete, followed by distillation to separate the product. The yield can be around 70-80% depending on the reaction conditions and purity of starting materials.

Ethyl 3-phenylpropanoate (CAS: 2021-28-5) is primarily used in the flavor and fragrance industry due to its pleasant aroma. It is also applied in the agrochemical industry as a precursor for the synthesis of certain herbicides. Additionally, it is utilized in the pharmaceutical industry for the production of certain drugs. In the cosmetic industry, it serves as a flavoring agent and a synthetic musk.

When handling Ethyl 3-phenylpropanoate (CAS: 2021-28-5), it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be handled in a well-ventilated area or under a fume hood to avoid inhalation of vapors. Spills should be cleaned up immediately with appropriate absorbents, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed information on storage, handling, and emergency procedures.