Compound Q&A

How is Ethyl 3-phenylpropanoate (CAS: 2021-28-5) typically synthesized?

Answer

Ethyl 3-phenylpropanoate
Ethyl 3-phenylpropanoate can be synthesized via an esterification reaction between phenylpropanol and ethyl acetate. Commonly, this reaction is catalyzed by sulfuric acid under reflux conditions. The process involves heating the mixture until the esterification is complete, followed by distillation to separate the product. The yield can be around 70-80% depending on the reaction conditions and purity of starting materials.

About

CAS No 2021-28-5
English Name Ethyl 3-phenylpropanoate
Molecular Formula C11H14O2
Molecular Weight 178.23 g/mol
SMILES CCOC(=O)CCc1ccccc1
InChIKey JAGZUIGGHGTFHO-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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