(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride (1:1)(CAS: 521284-22-0)

The compound (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride is a white crystalline solid with a molecular weight of approximately 343.8 g/mol. It has a pKa of about 5.5 and a solubility of 10 mg/mL in water. The compound is moderately reactive and can undergo hydrolysis under acidic conditions. It is soluble in common organic solvents like ethanol and acetone.

(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride can be synthesized via a multi-step process. One common method involves the reaction of 4-aminophenylacetic acid with (R)-1-phenylethanol followed by hydrochloric acid treatment. The reaction is carried out in an aqueous medium, and appropriate catalysts and solvents are used to ensure high yield and selectivity.

(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride is primarily used in the pharmaceutical industry due to its potential as an intermediate in the synthesis of medicinal compounds. It may also find applications in the polymer industry for the development of functional polymers, and in sensor technology for its ability to interact with specific analytes.

Proper handling of (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride requires the use of personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.