5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one(CAS: 1447-88-7)

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7) is a crystalline white powder with a molecular weight of approximately 347.24 g/mol. It is slightly soluble in water and more readily soluble in organic solvents like methanol. The compound is relatively stable under normal conditions but can be reactive to strong acids and bases. It exhibits limited solubility in common organic solvents and has a melting point around 220°C. It is also known for its ability to form complexes with various metal ions.

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7) is typically synthesized via a multistep process involving the condensation of 4-hydroxyacetophenone with 2,4-dihydroxybenzaldehyde followed by methylation and subsequent chromone formation. This process often employs Lewis acids as catalysts, with yields around 70-80%. The reaction conditions include the use of solvents such as acetic acid and heating under reflux for extended periods.

5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7) is primarily used in the pharmaceutical industry for the development of certain types of antibiotics and as an intermediate in the synthesis of other bioactive compounds. It also finds applications in the polymer industry for the preparation of advanced materials and in the manufacturing of sensors and semiconductors due to its unique electronic properties.

When handling 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one (CAS: 1447-88-7), it is crucial to wear personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In the event of a spill, it should be carefully cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions. This compound is not considered hazardous in terms of acute toxicity, but proper laboratory safety practices are essential.