m-PEG3-CH2CH2COOH(CAS: 67319-28-2)

m-PEG3-CH2CH2COOH is a water-soluble polymer with a molecular weight of approximately 10,000 Da. It has a crystalline form and is soluble in water and organic solvents. Reactivity is primarily observed in the carboxylic acid group, making it suitable for conjugation with other molecules. It exhibits good stability in aqueous solutions and is not flammable under normal conditions.

m-PEG3-CH2CH2COOH is synthesized through the modification of polyethylene glycol (PEG) using a coupling reagent such as N-hydroxysuccinimide (NHS) ester. The reaction involves the NHS ester reacting with the carboxylic acid group of the PEG, followed by the addition of a coupling agent to form the amide bond. This process yields a high-selectivity product with good yield.

m-PEG3-CH2CH2COOH is widely used in the pharmaceuticals industry for drug delivery systems, in the polymer industry for functionalization of polymers, in the sensor industry for biocompatible coatings, and in the semiconductor industry for surface modification of substrates. Its ability to form stable amide bonds with various functional groups makes it versatile in these applications.

When handling m-PEG3-CH2CH2COOH, it is important to use personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood. In case of skin contact, wash with soap and water. Ingestion should be avoided, and if ingested, seek medical attention immediately. An SDS (Safety Data Sheet) should be readily available for reference.